FOXO3 anticorps (N-Term)

N° du produit ABIN783540

Cet anticorps anti-FOXO3 est un anticorps Lapin Polyclonal détectant FOXO3 dans WB et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour FOXO3 anticorps (N-Term) (ABIN783540)

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-FOXO3 anticorps

Épitope: N-Term

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid peptide near the amino terminus of human FOXO3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur FOXO3

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: FOXO3 / FKHRL1

Sujet: FOXO3 is a ubiquitously expressed 75 kDa protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. FOXO3 is involved with mTOR in the regulation of autophagy in skeletal muscle, and activates protein degradation in atrophying muscle cells. FOXO3 has also been implicated in several neurodegenerative disorders including aging, neuromuscular disease, systemic lupus erythmatosus, stroke and diabetic complications.Synonyms: AF6q21 protein, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1

ID gène: 2309

NCBI Accession: NP_001446

UniProt: O43524

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis